PEX7 antibody (AA 180-260)

Catalog No. ABIN7223122

This anti-PEX7 antibody is a Rabbit Polyclonal antibody detecting PEX7 in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for PEX7 antibody (AA 180-260) (ABIN7223122)

Target: PEX7 (Peroxisomal Biogenesis Factor 7 (PEX7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PEX7 Antibody

Binding Specificity: AA 180-260

Purpose: Peroxin 7 Polyclonal Antibody

Specificity: Peroxin 7 Polyclonal Antibody detects endogenous levels of Peroxin 7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Peroxin 7 at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PEX7

Target: PEX7 (Peroxisomal Biogenesis Factor 7 (PEX7))

Alternative Name: Peroxin 7

Background: Rabbit Anti-Peroxin 7 Polyclonal Antibody,PEX7, PTS2R, Peroxisomal targeting signal 2 receptor, PTS2 receptor, Peroxin-7,PEX7 (peroxisomal biogenesis factor 7) encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in PEX7 cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD).,Peroxisomal targeting signal 2 receptor

Molecular Weight: observerd band 40kDa

Gene ID: 5191

UniProt: O00628

Pathways: Monocarboxylic Acid Catabolic Process