PEBP1 antibody (AA 71-120)
Quick Overview for PEBP1 antibody (AA 71-120) (ABIN7230514)
Target
See all PEBP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 71-120
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Purpose
- PBP Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PBP
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PBP protein at AA range: 71-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
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Alternative Name
- PBP
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Background
- Rabbit Anti-PBP Polyclonal Antibody,Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7,The protein encoded by PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. PPBP (Pro-Platelet Basic Protein) is a Protein Coding gene. Diseases associated with PPBP include Erythromelalgia and Essential Thrombocythemia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and p70S6K Signaling.,PBP
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Gene ID
- 5473
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UniProt
- P02775
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Pathways
- Feeding Behaviour
Target
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