PDE4B/C/D antibody

Catalog No. ABIN7216474

This Rabbit Polyclonal antibody specifically detects PDE4B/C/D in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PDE4B/C/D antibody (ABIN7216474)

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE4B/C/D antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDE4B/C/D Antibody

Purpose: PDE4B/C/D Polyclonal Antibody

Specificity: PDE4B/C/D Polyclonal Antibody detects endogenous levels of PDE4B/C/D protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PDE4B/C/D

Target: PDE4B/C/D (phosphodiesterase 4A/B/C, CAMP-Specific (PDE4B/C/D))

Alternative Name: PDE4B/C/D

Background: Rabbit Anti-PDE4B/C/D Polyclonal Antibody,PDE4B, DPDE4, cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, DPDE4, PDE32, PDE4C, DPDE1, cAMP-specific 3',5'-cyclic phosphodiesterase 4C, DPDE1, PDE21, PDE4D, DPDE3, cAMP-specific 3',5'-cyclic phosphodiesterase 4D, DPDE3, PDE43,PDE4D encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. PDE4D uses different promoters to generate multiple alternatively spliced transcript variants that encode functiona.,cAMP-specific 3',5'-cyclic phosphodiesterase 4D

Molecular Weight: observerd band 76kDa

Gene ID: 5144, 5142, 5143