PIK3R2 antibody (AA 1-60)

Catalog No. ABIN7230630

The Rabbit Polyclonal anti-PIK3R2 antibody is suitable to detect PIK3R2 in samples from Human, Rat and Mouse. It has been validated for ELISA and IHC (p).

Quick Overview for PIK3R2 antibody (AA 1-60) (ABIN7230630)

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIK3R2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PIK3R2 Antibody

Binding Specificity: AA 1-60

Purpose: PI 3-Kinase p85β Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PI 3-Kinase p85β

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PI 3-Kinase p85beta protein at AA range: 1-60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PIK3R2

Target: PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))

Alternative Name: PI 3-Kinase p85beta

Background: Rabbit Anti-PI 3-Kinase p85β Polyclonal Antibody,Phosphatidylinositol 3-kinase regulatory subunit beta, PI3-kinase regulatory subunit beta, PI3K regulatory subunit beta, PtdIns-3-kinase regulatory subunit beta, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, PI3-kinase subunit p85-beta, PtdIns-3-kinase regulatory subunit p85-beta,Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by PIK3R2 is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for PIK3R2. PIK3R2 (Phosphoinositide-3-Kinase Regulatory Subunit 2) is a Protein Coding gene. Diseases associated with PIK3R2 include Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome 1 and Mpph Syndrome. Among its related pathways are 4-1BB Pathway and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways.,PI 3-Kinase p85β

Gene ID: 5296

UniProt: O00459

Pathways: VEGF Signaling, BCR Signaling