PLA2G6 antibody (Internal Region)

Catalog No. ABIN7225342

The Rabbit Polyclonal anti-PLA2G6 antibody has been validated for WB and ELISA. It is suitable to detect PLA2G6 in samples from Human, Rat and Mouse.

Quick Overview for PLA2G6 antibody (Internal Region) (ABIN7225342)

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLA2G6 Antibody

Binding Specificity: Internal Region

Purpose: Group VI iPLA2 Polyclonal Antibody

Specificity: Group VI iPLA2 Polyclonal Antibody detects endogenous levels of Group VI iPLA2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Group VI iPLA2

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PLA2G6

Target: PLA2G6 (Phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6))

Alternative Name: Group VI iPLA2

Background: Rabbit Anti-Group VI iPLA2 Polyclonal Antibody,PLA2G6, PLPLA9, 85/88 kDa calcium-independent phospholipase A2, CaI-PLA2, Group VI phospholipase A2, GVI PLA2, Intracellular membrane-associated calcium-independent phospholipase A2 beta, iPLA2-beta, Patatin-like phospholipase domain-contai,The protein encoded by PLA2G6 (phospholipase A2 group VI) is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.,PLA2G6

Molecular Weight: observerd band 90kDa

Gene ID: 8398

UniProt: O60733

Pathways: Positive Regulation of Peptide Hormone Secretion