Plastin 3 antibody (AA 180-260)

Catalog No. ABIN7230702

This Rabbit Polyclonal antibody specifically detects Plastin 3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Plastin 3 antibody (AA 180-260) (ABIN7230702)

Target: Plastin 3 (PLS3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Plastin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Plastin 3 Antibody

Binding Specificity: AA 180-260

Purpose: PLS3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLS3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PLS3 protein at AA range: 180-260

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Plastin 3

Target: Plastin 3 (PLS3)

Alternative Name: PLS3

Background: Rabbit Anti-PLS3 Polyclonal Antibody,Phospholipid scramblase 3, PL scramblase 3, Ca(2+)-dependent phospholipid scramblase 3,May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.,PLS3

Molecular Weight: observerd band 32kDa

Gene ID: 57048

UniProt: Q9NRY6