PEAR1 antibody (AA 910-990)

Catalog No. ABIN7230580

The Rabbit Polyclonal anti-PEAR1 antibody is suitable to detect PEAR1 in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for PEAR1 antibody (AA 910-990) (ABIN7230580)

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEAR1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-PEAR1 Antibody

Binding Specificity: AA 910-990

Purpose: PEAR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PEAR1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PEAR1 protein at AA range: 910-990

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PEAR1

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Alternative Name: PEAR1

Background: Rabbit Anti-PEAR1 Polyclonal Antibody,Multiple epidermal growth factor-like domains protein 12, Multiple EGF-like domains protein 12,PEAR1 (Platelet Endothelial Aggregation Receptor 1) is a Protein Coding gene. Diseases associated with PEAR1 include Sticky Platelet Syndrome. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. An important paralog of this gene is MEGF10. When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation.,PEAR1

Molecular Weight: observerd band 114kDa

Gene ID: 375033

UniProt: Q5VY43