PVRL4 antibody (AA 290-370)

Catalog No. ABIN7225202

This Rabbit Polyclonal antibody specifically detects PVRL4 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PVRL4 antibody (AA 290-370) (ABIN7225202)

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PVRL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PVRL4 Antibody

Binding Specificity: AA 290-370

Purpose: Nectin 4 Polyclonal Antibody

Specificity: Nectin 4 Polyclonal Antibody detects endogenous levels of Nectin 4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Nectin 4 at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PVRL4

Target: PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))

Alternative Name: Nectin 4

Background: Rabbit Anti-Nectin 4 Polyclonal Antibody,PVRL4, LNIR, PRR4, Poliovirus receptor-related protein 4, Ig superfamily receptor LNIR, Nectin-4,NECTIN4 (nectin cell adhesion molecule 4) encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in NECTIN4 are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.,Poliovirus receptor-related protein 4

Molecular Weight: observerd band 55kDa

Gene ID: 81607

UniProt: Q96NY8

Pathways: Cell-Cell Junction Organization