PAOX antibody (AA 260-340)

Catalog No. ABIN7217746

The Rabbit Polyclonal anti-PAOX antibody (ABIN7217746) specifically detects PAOX in WB, ELISA, IHC and IF. The antibody is reactive with Mouse and Human samples.

Quick Overview for PAOX antibody (AA 260-340) (ABIN7217746)

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PAOX Antibody

Binding Specificity: AA 260-340

Purpose: Rabbit Anti-PAOX Polyclonal Antibody

Specificity: PAOX Polyclonal Antibody detects endogenous levels of PAOX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PAOX at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PAOX

Target: PAOX (Polyamine Oxidase (Exo-N4-Amino) (PAOX))

Alternative Name: PAOX

Background: PAOX, PAO, Peroxisomal N(1)-acetyl-spermine/spermidine oxidase, Polyamine oxidasePAOX (Polyamine Oxidase (Exo-N4-Amino)) is a Protein Coding gene. Among its related pathways are Metabolism and cytochrome P450. Gene Ontology (GO) annotations related to this gene include receptor binding and polyamine oxidase activity. An important paralog of this gene is KDM1B. Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: n(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.

Molecular Weight: 70kD

Gene ID: 196743

UniProt: Q6QHF9