PNKP antibody (AA 50-130)
Quick Overview for PNKP antibody (AA 50-130) (ABIN7230720)
Target
See all PNKP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 50-130
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Purpose
- PNKP Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PNKP protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PNKP protein at AA range: 50-130
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Alternative Name
- PNKP
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Background
- Rabbit Anti-PNKP Polyclonal Antibody,Bifunctional polynucleotide phosphatase/kinase, DNA 5'-kinase/3'-phosphatase, Polynucleotide kinase-3'-phosphatase, Polynucleotide 3'-phosphatase, 2'(3')-polynucleotidase, Polynucleotide 5'-hydroxyl-kinase,PNKP (Polynucleotide Kinase 3'-Phosphatase) is a Protein Coding gene. Diseases associated with PNKP includeAtaxia-Oculomotor Apraxia 4andMicrocephaly, Seizures, And Developmental Delay. Among its related pathways areDNA DamageandDNA damage_NHEJ mechanisms of DSBs repair.,PNKP
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Molecular Weight
- observerd band 57kDa
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Gene ID
- 11284
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UniProt
- Q96T60
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Pathways
- DNA Damage Repair, Nucleotide Phosphorylation
Target
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