KCNT1 antibody (AA 980-1060)

Catalog No. ABIN7223804

This anti-KCNT1 antibody is a Rabbit Polyclonal antibody detecting KCNT1 in WB, ELISA and IHC (p). Suitable for Human, Rat and Mouse.

Quick Overview for KCNT1 antibody (AA 980-1060) (ABIN7223804)

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-KCNT1 Antibody

Binding Specificity: AA 980-1060

Purpose: KCNT1 Polyclonal Antibody

Specificity: KCNT1 Polyclonal Antibody detects endogenous levels of KCNT1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human KCNT1 at AA range: 980-1060

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for KCNT1

Target: KCNT1 (Potassium Channel, Subfamily T, Member 1 (KCNT1))

Alternative Name: KCNT1

Background: Rabbit Anti-KCNT1 Polyclonal Antibody,KCNT1, KIAA1422, Potassium channel subfamily T member 1, KCa4.1,Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNT1 (potassium sodium-activated channel subfamily T member 1) encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in KCNT1 cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants.,Potassium channel subfamily T member 1

Molecular Weight: observerd band 140kDa

Gene ID: 57582

UniProt: Q5JUK3