Kv2.1/KCNB1 antibody

Catalog No. ABIN7221980

This Rabbit Polyclonal antibody specifically detects Kv2.1/KCNB1 in ELISA and WB. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for Kv2.1/KCNB1 antibody (ABIN7221980)

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv2.1/KCNB1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-Kv2.1/KCNB1 Antibody

Purpose: KV2.1 Polyclonal Antibody

Specificity: KV2.1 Polyclonal Antibody detects endogenous levels of KV2.1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human KV2.1 around the non-phosphorylation site of S805

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Kv2.1/KCNB1

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Alternative Name: KV2.1

Background: Rabbit Anti-KV2.1 Polyclonal Antibody,KCNB1, Potassium voltage-gated channel subfamily B member 1, Delayed rectifier potassium channel 1, DRK1, h-DRK1, Voltage-gated potassium channel subunit Kv2.1,Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). KCNB1 encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel and its activity is modulated by some other family members.,Potassium voltage-gated channel subfamily B member 1

Molecular Weight: observerd band 90kDa

Gene ID: 3745

UniProt: Q14721

Pathways: Synaptic Membrane