Kv3.4 antibody

Catalog No. ABIN7215570

This Rabbit Polyclonal antibody specifically detects Kv3.4 in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for Kv3.4 antibody (ABIN7215570)

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv3.4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Kv3.4 Antibody

Purpose: Kv3.4 Polyclonal Antibody

Specificity: Kv3.4 Polyclonal Antibody detects endogenous levels of Kv3.4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Kv3.4 around the non-phosphorylation site of S15

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Kv3.4

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Alternative Name: Kv3.4

Background: Rabbit Anti-Kv3.4 Polyclonal Antibody,KCNC4, Potassium voltage-gated channel subfamily C member 4, KSHIIIC, Voltage-gated potassium channel subunit Kv3.4,The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, KCNC4 is similar to the Shaw subfamily. Potassium voltage-gated channel subfamily C member 4 encoded by KCNC4 belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene.,Potassium voltage-gated channel subfamily C member 4

Molecular Weight: observerd band 70kDa

Gene ID: 3749

UniProt: Q03721