PP2A-B56-alpha (AA 290-370) antibody

Catalog No. ABIN7223404

This Rabbit Polyclonal antibody specifically detects PP2A-B56-alpha in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PP2A-B56-alpha (AA 290-370) antibody (ABIN7223404)

Target: PP2A-B56-alpha

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details

Binding Specificity: AA 290-370

Purpose: PP2A-B56-α Polyclonal Antibody

Specificity: PP2A-B56-α Polyclonal Antibody detects endogenous levels of PP2A-B56-α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PP2A-B56-alpha at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: PP2A-B56-alpha

Background: Rabbit Anti-PP2A-B56-α Polyclonal Antibody,PPP2R5A, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform, PP2A B subunit isoform B'-alpha, PP2A B subunit isoform B56-alpha, PP2A B subunit isoform PR61-alpha, PR61alpha, PP2A B subunit isoform R5-alpha,The product of PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha) belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. PPP2R5A encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for PPP2R5A.,serine threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform

Molecular Weight: observerd band 57kDa

Gene ID: 5525

UniProt: Q15172