PP2A-B56-delta (AA 520-600) antibody

Catalog No. ABIN7223406

The Rabbit Polyclonal anti-PP2A-B56-delta antibody is suitable to detect PP2A-B56-delta in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IHC (p).

Quick Overview for PP2A-B56-delta (AA 520-600) antibody (ABIN7223406)

Target: PP2A-B56-delta

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details

Binding Specificity: AA 520-600

Purpose: PP2A-B56-δ Polyclonal Antibody

Specificity: PP2A-B56-δ Polyclonal Antibody detects endogenous levels of PP2A-B56-δ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human PP2A-B56-delta at AA range: 520-600

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details

Target: PP2A-B56-delta

Background: Rabbit Anti-PP2A-B56-δ Polyclonal Antibody,PPP2R5D, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, PP2A B subunit isoform B'-delta, PP2A B subunit isoform B56-delta, PP2A B subunit isoform PR61-delta, PP2A B subunit isoform R5-delta,The product of PPP2R5D (protein phosphatase 2 regulatory subunit B'delta) belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. PPP2R5D encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.,serine threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

Molecular Weight: observerd band 70kDa

Gene ID: 5528

UniProt: Q14738