PSG3 antibody (Internal Region)

Catalog No. ABIN7223672

This Rabbit Polyclonal antibody specifically detects PSG3 in ELISA, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PSG3 antibody (Internal Region) (ABIN7223672)

Target: PSG3 (Pregnancy Specific beta-1-Glycoprotein 3 (PSG3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSG3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PSG3 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-PSG3 Polyclonal Antibody

Specificity: PSG3 Polyclonal Antibody detects endogenous levels of PSG3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PSG3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PSG3

Target: PSG3 (Pregnancy Specific beta-1-Glycoprotein 3 (PSG3))

Alternative Name: PSG3

Background: PSG3, Pregnancy-specific beta-1-glycoprotein 3, PS-beta-G-3, PSBG-3, Pregnancy-specific glycoprotein 3, Carcinoembryonic antigen SG5The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al. 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).

Gene ID: 5671

UniProt: Q16557