Prokineticin Receptor 1 antibody (AA 30-110)

Catalog No. ABIN7216600

This Rabbit Polyclonal antibody specifically detects Prokineticin Receptor 1 in ELISA, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Prokineticin Receptor 1 antibody (AA 30-110) (ABIN7216600)

Target: Prokineticin Receptor 1 (PROKR1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prokineticin Receptor 1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Prokineticin Receptor 1 Antibody

Binding Specificity: AA 30-110

Purpose: PKR1 Polyclonal Antibody

Specificity: PKR1 Polyclonal Antibody detects endogenous levels of PKR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human PKR1 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Prokineticin Receptor 1

Target: Prokineticin Receptor 1 (PROKR1)

Alternative Name: PKR1

Background: Rabbit Anti-PKR1 Polyclonal Antibody,PROKR1, GPR73, PKR1, Prokineticin receptor 1, PK-R1, G-protein coupled receptor 73, G-protein coupled receptor ZAQ, GPR73a,PROKR1 encodes a member of the G-protein-coupled receptor family. prokineticin receptor 1 binds to prokineticins (1 and 2), leading to the activation of MAPK and STAT signaling pathways. Prokineticins are protein ligands involved in angiogenesis and inflammation. Prokineticin receptor 1 is expressed in peripheral tissues such as those comprising the circulatory system, lungs, reproductive system, endocrine system and the gastrointestinal system. Prokineticin receptor 1 may be involved in signaling in human fetal ovary during initiation of primordial follicle formation. Sequence variants in PROKR1 may be associated with recurrent miscarriage.,Prokineticin receptor 1

Molecular Weight: observerd band 45kDa

Gene ID: 10887

UniProt: Q8TCW9

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma