PSMD14 antibody

Catalog No. ABIN7225326

The Rabbit Polyclonal anti-PSMD14 antibody has been validated for ELISA and IF. It is suitable to detect PSMD14 in samples from Human.

Quick Overview for PSMD14 antibody (ABIN7225326)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD14 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-PSMD14 Antibody

Purpose: MAD1 Polyclonal Antibody

Specificity: MAD1 Polyclonal Antibody detects endogenous levels of MAD1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human MAD1 around the non-phosphorylation site of S428

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Alternative Name: MAD1

Background: Rabbit Anti-MAD1 Polyclonal Antibody,MAD1L1, MAD1, TXBP181, Mitotic spindle assembly checkpoint protein MAD1, Mitotic arrest deficient 1-like protein 1, MAD1-like protein 1, Mitotic checkpoint MAD1 protein homolog, HsMAD1, hMAD1, Tax-binding protein 181,MAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.,Mitotic spindle assembly checkpoint protein MAD1

Gene ID: 8379

UniProt: Q9Y6D9

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway