PSMD14 antibody

Catalog No. ABIN108606

Cited in 3+ publications. The Mouse Monoclonal anti-PSMD14 antibody (Clone 9B10) (ABIN108606) specifically detects PSMD14 in IF, ICC, FACS and IP. The antibody is reactive with Human samples.

Quick Overview for PSMD14 antibody (ABIN108606)

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PSMD14 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 9B10

Product Details anti-PSMD14 Antibody

Purpose: Mad1 Monoclonal Antibody [9B10]

Purification: Protein A

Immunogen: Recombinant full length Mad1 protein (human)

Isotype: IgG2b

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try, IF: 1/500 - 1/1000. IP: Use at a concentration of 5 μg/0.5 - 1 mL of extract

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-PSMD14 antibody (ABIN108606)

Sartorius, DApice, Trovato, Cuccaro, Costa, De Leo, Marzullo, Biondo, DAuria, De Matteis, Ciccodicola, De Berardinis: "Antigen delivery by filamentous bacteriophage fd displaying an anti-DEC-205 single-chain variable fragment confers adjuvanticity by triggering a TLR9-mediated immune response." in: EMBO molecular medicine, Vol. 7, Issue 7, pp. 973-88, (2015) (PubMed).

Hewitt, Tighe, Santaguida, White, Jones, Musacchio, Green, Taylor: "Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complex." in: The Journal of cell biology, Vol. 190, Issue 1, pp. 25-34, (2010) (PubMed).

Weaver, Bonday, Putkey, Kops, Silk, Cleveland: "Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss." in: The Journal of cell biology, Vol. 162, Issue 4, pp. 551-63, (2003) (PubMed).

Target Details for PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Alternative Name: Mad1

Background: HMAD1 antibody,HsMAD1 antibody,MAD-1 antibody,MAD1L1 antibody,Mitotic arrest deficient 1antibody,Mitotic checkpoint MAD1 protein homolog antibody,Mitotic spindle assembly checkpoint protein MAD1antibody,PIG-9 antibody,PIG9 antibody,Tax binding protein 181 antibody,TP53I9 antibody,Tumor protein p53inducible protein 9 antibody,TXBP181 antibody

Gene ID: 8379

OMIM: 602686

UniProt: Q9Y6D9

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway