PROS1 antibody (AA 20-100)
Quick Overview for PROS1 antibody (AA 20-100) (ABIN7230792)
Target
See all PROS1 (PROS) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 20-100
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Purpose
- PROS Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PROS protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PROS protein at AA range: 20-100
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PROS1 (PROS) (Protein S (PROS))
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Alternative Name
- PROS
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Background
- Rabbit Anti-PROS Polyclonal Antibody,Vitamin K-dependent protein S,PROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in PROS1 result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.,PROS
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Molecular Weight
- observerd band 74kDa
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Gene ID
- 5627
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UniProt
- P07225
Target
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