PTK6 antibody (AA 10-90)
Quick Overview for PTK6 antibody (AA 10-90) (ABIN7223796)
Target
See all PTK6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 10-90
-
Purpose
- Brk Polyclonal Antibody
-
Specificity
- Brk Polyclonal Antibody detects endogenous levels of Brk protein.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
-
Immunogen
- Synthesized peptide derived from the N-terminal region of human Brk at AA range: 10-90
-
Isotype
- IgG
-
-
-
-
Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
-
Comment
-
Primary Antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
-
- PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))
-
Alternative Name
- Brk
-
Background
- Rabbit Anti-Brk Polyclonal Antibody,PTK6, BRK, Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK,The protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.,Protein-tyrosine kinase 6
-
Molecular Weight
- observerd band 48kDa
-
Gene ID
- 5753
-
UniProt
- Q13882
Target
-