PWWP2B antibody (AA 240-320)

Catalog No. ABIN7220034

This Rabbit Polyclonal antibody specifically detects PWWP2B in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PWWP2B antibody (AA 240-320) (ABIN7220034)

Target: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PWWP2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PWWP2B Antibody

Binding Specificity: AA 240-320

Purpose: PWWP2B Polyclonal Antibody

Specificity: PWWP2B Polyclonal Antibody detects endogenous levels of PWWP2B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human PWWP2B at AA range: 240-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PWWP2B

Target: PWWP2B (PWWP Domain Containing 2B (PWWP2B))

Alternative Name: PWWP2B

Background: Rabbit Anti-PWWP2B Polyclonal Antibody,PWWP2B, PWWP2, PWWP domain-containing protein 2B,PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.,PWWP domain-containing protein 2B

Molecular Weight: observerd band 64kDa

Gene ID: 170394

UniProt: Q6NUJ5