RAB33B antibody (AA 100-180)

Catalog No. ABIN7230960

This Rabbit Polyclonal antibody specifically detects RAB33B in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RAB33B antibody (AA 100-180) (ABIN7230960)

Target: RAB33B (RAB33B, Member RAS Oncogene Family (RAB33B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB33B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB33B Antibody

Binding Specificity: AA 100-180

Purpose: RB33B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RB33B protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RB33B protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RAB33B

Target: RAB33B (RAB33B, Member RAS Oncogene Family (RAB33B))

Alternative Name: RB33B

Background: Rabbit Anti-RB33B Polyclonal Antibody,Ras-related protein Rab-33B,RAB33B (RAB33B, Member RAS Oncogene Family) encodes a small GTP-binding protein of the Rab GTPase family, whose members function in vesicle transport during protein secretion and endocytosis. Rab GTPases are active, membrane-associated proteins that recruit effector proteins in the GTP-bound state and inactive cytosolic proteins when in a GDP-bound state. The protein encoded by RAB33B is ubiquitously expressed and has been implicated in Golgi to endoplasmic reticulum cycling of Golgi enzymes. In addition, this protein regulates Golgi homeostasis and coordinates intra-Golgi retrograde trafficking. Allelic variants in RAB33B have been associated with Dyggve-Melchior-Clausen syndrome and Smith-McCort dysplasia 2, which are autosomal recessive spondyloepimetaphyseal dysplasias characterized by skeletal abnormalities.,RB33B

Molecular Weight: observerd band 25kDa

Gene ID: 83452

UniProt: Q9H082