RANBP17 antibody (AA 120-200)

Catalog No. ABIN7224328

The Rabbit Polyclonal anti-RANBP17 antibody is suitable to detect RANBP17 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RANBP17 antibody (AA 120-200) (ABIN7224328)

Target: RANBP17 (RAN Binding Protein 17 (RANBP17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RANBP17 Antibody

Binding Specificity: AA 120-200

Purpose: Ran BP-17 Polyclonal Antibody

Specificity: Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Ran BP-17 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RANBP17

Target: RANBP17 (RAN Binding Protein 17 (RANBP17))

Alternative Name: Ran BP-17

Background: Rabbit Anti-Ran BP-17 Polyclonal Antibody,RANBP17, Ran-binding protein 17,The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex, see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.,Ran-binding protein 17

Molecular Weight: observerd band 125kDa

Gene ID: 64901

UniProt: Q9H2T7

Pathways: Protein targeting to Nucleus