RAPGEF4 antibody (AA 240-320)

Catalog No. ABIN7231164

The Rabbit Polyclonal anti-RAPGEF4 antibody has been validated for WB and ELISA. It is suitable to detect RAPGEF4 in samples from Human, Mouse and Rat.

Quick Overview for RAPGEF4 antibody (AA 240-320) (ABIN7231164)

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAPGEF4 Antibody

Binding Specificity: AA 240-320

Purpose: RPGF4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPGF4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RPGF4 protein at AA range: 240-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RAPGEF4

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Alternative Name: RPGF4

Background: Rabbit Anti-RPGF4 Polyclonal Antibody,Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFII,RAPGEF4 (Rap Guanine Nucleotide Exchange Factor 4) is a Protein Coding gene. Diseases associated with RAPGEF4 include Lesch-Nyhan Syndrome and Acrodysostosis. Among its related pathways are Rap1 signalling and Metabolism. GO annotations related to RAPGEF4 include guanyl-nucleotide exchange factor activity and Ras GTPase binding. An important paralog of RAPGEF4 is RAPGEF3.,RPGF4

Molecular Weight: observerd band 111kDa

Gene ID: 11069

UniProt: Q8WZA2

Pathways: Hormone Transport, Smooth Muscle Cell Migration