RASGRP3 antibody (AA 90-170)

Catalog No. ABIN7228802

This anti-RASGRP3 antibody is a Rabbit Polyclonal antibody detecting RASGRP3 in WB and ELISA. Suitable for Human.

Quick Overview for RASGRP3 antibody (AA 90-170) (ABIN7228802)

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASGRP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASGRP3 Antibody

Binding Specificity: AA 90-170

Purpose: GRP3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GRP3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human GRP3 protein at AA range: 90-170

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RASGRP3

Target: RASGRP3 (RAS Guanyl Releasing Protein 3 (Calcium and DAG-Regulated) (RASGRP3))

Alternative Name: GRP3

Background: Rabbit Anti-GRP3 Polyclonal Antibody,Ras guanyl-releasing protein 3, Calcium and DAG-regulated guanine nucleotide exchange factor III, Guanine nucleotide exchange factor for Rap1,RASGRP3 (RAS Guanyl Releasing Protein 3) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling TC21 regulation pathway. GO annotations related to RASGRP3 include calcium ion binding and GTPase activator activity. The protein encoded by RASGRP3 is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in RASGRP3 have been associated with systemic lupus erythematosus and several cancers.,GRP3

Molecular Weight: observerd band 75kDa

Gene ID: 25780

UniProt: Q8IV61