RHOQ antibody (AA 60-140)
Quick Overview for RHOQ antibody (AA 60-140) (ABIN7231052)
Target
See all RHOQ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 60-140
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Purpose
- RHOQ Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of RHOQ protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human RHOQ protein at AA range: 60-140
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RHOQ (Ras Homolog Gene Family, Member Q (RHOQ))
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Alternative Name
- RHOQ
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Background
- Rabbit Anti-RHOQ Polyclonal Antibody,Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7A,RHOQ (Ras Homolog Family Member Q) encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.,RHOQ
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Molecular Weight
- observerd band 22kDa
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Gene ID
- 23433
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UniProt
- P17081
Target
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