RASIP1 antibody (AA 620-700)

Catalog No. ABIN7230920

This anti-RASIP1 antibody is a Rabbit Polyclonal antibody detecting RASIP1 in WB and ELISA. Suitable for Human.

Quick Overview for RASIP1 antibody (AA 620-700) (ABIN7230920)

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASIP1 Antibody

Binding Specificity: AA 620-700

Purpose: RAIN Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RAIN protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RAIN protein at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RASIP1

Target: RASIP1 (Ras Interacting Protein 1 (RASIP1))

Alternative Name: RAIN

Background: Rabbit Anti-RAIN Polyclonal Antibody,Ras-interacting protein 1, Rain,Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy.,RAIN

Molecular Weight: observerd band 105kDa

Gene ID: 54922

UniProt: Q5U651