RASA4 antibody (AA 100-180)

Catalog No. ABIN7230954

This Rabbit Polyclonal antibody specifically detects RASA4 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for RASA4 antibody (AA 100-180) (ABIN7230954)

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RASA4 Antibody

Binding Specificity: AA 100-180

Purpose: RASL2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RASL2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RASL2 protein at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RASA4

Target: RASA4 (RAS P21 Protein Activator 4 (RASA4))

Alternative Name: RASL2

Background: Rabbit Anti-RASL2 Polyclonal Antibody,Ras GTPase-activating protein 4, Calcium-promoted Ras inactivator, Ras p21 protein activator 4, RasGAP-activating-like protein 2,RASA4 (RAS P21 Protein Activator 4) encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca(2+). Stimuli that increase intracellular Ca(2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for RASA4.,RASL2

Molecular Weight: observerd band 88kDa

Gene ID: 10156

UniProt: O43374