RIT2 antibody

Catalog No. ABIN7231070

The Rabbit Polyclonal anti-RIT2 antibody is suitable to detect RIT2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for RIT2 antibody (ABIN7231070)

Target: RIT2 (Ras-Like Without CAAX 2 (RIT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RIT2 Antibody

Purpose: RIT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RIT2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RIT2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RIT2

Target: RIT2 (Ras-Like Without CAAX 2 (RIT2))

Alternative Name: RIT2

Background: Rabbit Anti-RIT2 Polyclonal Antibody,GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2,RIN belongs to the RAS (HRAS, MIM 190020) superfamily of small GTPases (Shao et al. 1999 [PubMed 10545207]). RIT2 (Ras Like Without CAAX 2) is a Protein Coding gene. Diseases associated with RIT2 include Ehrlichiosis and Parkinson Disease Susceptibility. Among its related pathways are RET signaling and Neurotrophic factor-mediated Trk receptor signaling.,RIT2

Molecular Weight: observerd band 23kDa

Gene ID: 6014

UniProt: Q99578

Pathways: Neurotrophin Signaling Pathway