RRAGB antibody (AA 50-130)

Catalog No. ABIN7218968

The Rabbit Polyclonal anti-RRAGB antibody is suitable to detect RRAGB in samples from Human, Mouse and Rat. It has been validated for ELISA and IHC (p).

Quick Overview for RRAGB antibody (AA 50-130) (ABIN7218968)

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAGB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RRAGB Antibody

Binding Specificity: AA 50-130

Purpose: Rag B Polyclonal Antibody

Specificity: Rag B Polyclonal Antibody detects endogenous levels of Rag B protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Rag B at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RRAGB

Target: RRAGB (Ras-Related GTP Binding B (RRAGB))

Alternative Name: Rag B

Background: Rabbit Anti-Rag B Polyclonal Antibody,RRAGB, Ras-related GTP-binding protein B, Rag B, RagB,Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.,Ras-related GTP-binding protein B

Gene ID: 10325

UniProt: Q5VZM2