BRCAA1 antibody (Internal Region)

Catalog No. ABIN7213842

This Rabbit Polyclonal antibody specifically detects BRCAA1 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for BRCAA1 antibody (Internal Region) (ABIN7213842)

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRCAA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRCAA1 Antibody

Binding Specificity: Internal Region

Purpose: BRCAA1 Polyclonal Antibody

Specificity: BRCAA1 Polyclonal Antibody detects endogenous levels of BRCAA1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human BRCAA1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for BRCAA1

Target: BRCAA1 (ARID4B) (RBP1-like protein (ARID4B))

Alternative Name: BRCAA1

Background: Rabbit Anti-BRCAA1 Polyclonal Antibody,ARID4B, BRCAA1, RBBP1L1, RBP1L1, SAP180, AT-rich interactive domain-containing protein 4B, ARID domain-containing protein 4B, 180 kDa Sin3-associated polypeptide, Sin3-associated polypeptide p180, Breast cancer-associated antigen BRCAA1, Hi,ARID4B encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein (AT-rich interaction domain 4B) is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized.,AT-rich interactive domain-containing protein 4B

Molecular Weight: observerd band 148kDa

Gene ID: 51742

UniProt: Q4LE39