RGS14 antibody (AA 100-180)

Catalog No. ABIN7219096

This anti-RGS14 antibody is a Rabbit Polyclonal antibody detecting RGS14 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for RGS14 antibody (AA 100-180) (ABIN7219096)

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS14 Antibody

Binding Specificity: AA 100-180

Purpose: RGS14 Polyclonal Antibody

Specificity: RGS14 Polyclonal Antibody detects endogenous levels of RGS14 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human RGS14 at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Alternative Name: RGS14

Background: Rabbit Anti-RGS14 Polyclonal Antibody,RGS14, Regulator of G-protein signaling 14, RGS14,RGS14 encodes a member of the regulator of G-protein signaling family. Regulator of G-protein signaling 14 contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.,Regulator of G-protein signaling 14

Molecular Weight: observerd band 65kDa

Gene ID: 10636

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling