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RGS14 antibody (AA 504-516)

RGS14 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN784000
  • Target See all RGS14 Antibodies
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 504-516
    Reactivity
    • 46
    • 33
    • 25
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 4
    • 1
    Rabbit
    Clonality
    • 60
    • 2
    Polyclonal
    Conjugate
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This RGS14 antibody is un-conjugated
    Application
    • 51
    • 24
    • 13
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    Recognizes RGS14.
    Cellular Localization: Membrane
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Antigen-Affinity Chromatography.
    Immunogen
    Synthetic peptide contain a sequence corresponding to a region within amino acids 504 and 516 of Human RGS14
    Isotype
    IgG
    Top Product
    Discover our top product RGS14 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.93 mg/mL
    Buffer
    0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.
    Preservative
    Thimerosal (Merthiolate)
    Precaution of Use
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody undiluted (in aliquots) at -20 °C.
  • Target
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Alternative Name
    RGS14 (RGS14 Products)
    Synonyms
    RPIP1 antibody, MGC80558 antibody, RGS14 antibody, rgs14 antibody, wu:fi04g12 antibody, regulator of G protein signaling 14 antibody, regulator of G-protein signaling 14 antibody, regulator of G-protein signaling 14 L homeolog antibody, regulator of G-protein signalling 14 antibody, regulator of G protein signaling 14a antibody, RGS14 antibody, Rgs14 antibody, rgs14.L antibody, rgs14 antibody, rgs14a antibody
    Background
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.Synonyms: Regulator of G-protein signaling 14
    Gene ID
    10636, 9606
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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