RGS4 antibody (AA 80-160)

Catalog No. ABIN7231032

This Rabbit Polyclonal antibody specifically detects RGS4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RGS4 antibody (AA 80-160) (ABIN7231032)

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RGS4 Antibody

Binding Specificity: AA 80-160

Purpose: RGS4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RGS4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RGS4 protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RGS4

Target: RGS4 (Regulator of G-Protein Signaling 4 (RGS4))

Alternative Name: RGS4

Background: Rabbit Anti-RGS4 Polyclonal Antibody,Regulator of G-protein signaling 4, RGP4, RGS4,RGS4 (Regulator Of G Protein Signaling 4) is a Protein Coding gene. Diseases associated with RGS4 include Schizophrenia 9 and Schizophrenia. Among its related pathways are Signaling by GPCR and ADP signalling through P2Y purinoceptor 12. Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37 % identical to RGS1 and 97 % identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm. Alternatively spliced transcript variants have been found for RGS4.,RGS4

Molecular Weight: observerd band 22kDa

Gene ID: 5999

UniProt: P49798

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling