MSK2 antibody (pThr568)
Quick Overview for MSK2 antibody (pThr568) (ABIN7225750)
Target
See all MSK2 (RPS6KA4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pThr568
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Purpose
- MSK2 (phospho Thr568) Polyclonal Antibody
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Specificity
- Phospho-MSK2 (T568) Polyclonal Antibody detects endogenous levels of MSK2 protein only when phosphorylated at T568.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human MSK2 Phospho-Thr568
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- MSK2 (RPS6KA4) (Ribosomal Protein S6 Kinase A4 (RPS6KA4))
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Alternative Name
- MSK2
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Background
- Rabbit Anti-MSK2 (phospho Thr568) Polyclonal Antibody,RPS6KA4, MSK2, Ribosomal protein S6 kinase alpha-4, S6K-alpha-4, 90 kDa ribosomal protein S6 kinase 4, Nuclear mitogen- and stress-activated protein kinase 2, Ribosomal protein kinase B, RSKB,RPS6KA4 (ribosomal protein S6 kinase A4) encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also phosphorylate histone H3 to regulate certain inflammatory genes. Several transcript variants encoding different isoforms have been found for RPS6KA4.,Ribosomal protein S6 kinase alpha-4
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Molecular Weight
- observerd band 95kDa
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Gene ID
- 8986
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UniProt
- O75676
Target
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