RIP2 antibody

Catalog No. ABIN7225650

The Rabbit Polyclonal anti-RIP2 antibody has been validated for WB, ELISA and IHC (p). It is suitable to detect RIP2 in samples from Human and Mouse.

Quick Overview for RIP2 antibody (ABIN7225650)

Target: RIP2 (ROP Interactive Partner 2 (RIP2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RIP2 Antibody

Purpose: RIP2 Polyclonal Antibody

Specificity: RIP2 Polyclonal Antibody detects endogenous levels of RIP2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human RIP2 around the non-phosphorylation site of S176

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RIP2

Target: RIP2 (ROP Interactive Partner 2 (RIP2))

Alternative Name: RIP2

Background: Rabbit Anti-RIP2 Polyclonal Antibody,RIPK2, CARDIAK, RICK, RIP2, Receptor-interacting serine/threonine-protein kinase 2, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP-like-interacting CLARP kinase, Receptor-in,RIPK2 (receptor interacting serine/threonine kinase 2) encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.,Receptor-interacting serine threonine-protein kinase 2

Molecular Weight: observerd band 61kDa

Gene ID: 8767

UniProt: O43353

Pathways: TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades