RRN3 antibody (pSer649)

Catalog No. ABIN7223310

This anti-RRN3 antibody is a Rabbit Polyclonal antibody detecting RRN3 in WB, ELISA and IHC (p). Suitable for Human.

Quick Overview for RRN3 antibody (pSer649) (ABIN7223310)

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRN3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RRN3 Antibody

Binding Specificity: pSer649

Purpose: Rrn3 (phospho Ser649) Polyclonal Antibody

Specificity: Phospho-Rrn3 (S649) Polyclonal Antibody detects endogenous levels of Rrn3 protein only when phosphorylated at S649.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Rrn3 Phospho-Ser649

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RRN3

Target: RRN3 (RRN3 RNA Polymerase I Transcription Factor (RRN3))

Alternative Name: Rrn3

Background: Rabbit Anti-Rrn3 (phospho Ser649) Polyclonal Antibody,RRN3, TIFIA, RNA polymerase I-specific transcription initiation factor RRN3, Transcription initiation factor IA, TIF-IA,RRN3 (RRN3 Homolog, RNA Polymerase I Transcription Factor) is a Protein Coding gene. Among its related pathways are Gene Expression and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. GO annotations related to this gene include binding and RNA polymerase binding.,RNA polymerase I-specific transcription initiation factor RRN3

Molecular Weight: observerd band 70kDa

Gene ID: 54700

UniProt: Q9NYV6

Pathways: Negative Regulation of intrinsic apoptotic Signaling