SAMHD1 antibody (Internal Region)

Catalog No. ABIN7218500

The Rabbit Polyclonal anti-SAMHD1 antibody is suitable to detect SAMHD1 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for SAMHD1 antibody (Internal Region) (ABIN7218500)

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMHD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SAMHD1 Antibody

Binding Specificity: Internal Region

Purpose: SAMHD1 Polyclonal Antibody

Specificity: SAMHD1 Polyclonal Antibody detects endogenous levels of SAMHD1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human SAMHD1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SAMHD1

Target: SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))

Alternative Name: SAMHD1

Background: Rabbit Anti-SAMHD1 Polyclonal Antibody,SAMHD1, MOP5, SAM domain and HD domain-containing protein 1, Dendritic cell-derived IFNG-induced protein, DCIP, Monocyte protein 5, MOP-5,SAMHD1 may play a role in regulation of the innate immune response. The SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.,SAM domain and HD domain-containing protein 1

Molecular Weight: observerd band 72kDa

Gene ID: 25939

UniProt: Q9Y3Z3