SCO2 antibody (AA 181-230)

Catalog No. ABIN7231290

This anti-SCO2 antibody is a Rabbit Polyclonal antibody detecting SCO2 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for SCO2 antibody (AA 181-230) (ABIN7231290)

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SCO2 Antibody

Binding Specificity: AA 181-230

Purpose: SCO2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SCO2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SCO2 protein at AA range: 181-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SCO2

Target: SCO2 (SCO2 Cytochrome C Oxidase Assembly Protein (SCO2))

Alternative Name: SCO2

Background: Rabbit Anti-SCO2 Polyclonal Antibody,Protein SCO2 homolog, mitochondrial,Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors, SCO2 encodes one of the COX assembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in SCO2 are associated with fatal infantile encephalocardiomyopathy and myopia 6.,SCO2

Molecular Weight: observerd band 29kDa

Gene ID: 9997

UniProt: O43819

Pathways: Transition Metal Ion Homeostasis, Warburg Effect