SCRIB antibody

Catalog No. ABIN7231292

The Rabbit Polyclonal anti-SCRIB antibody has been validated for WB and ELISA. It is suitable to detect SCRIB in samples from Human.

Quick Overview for SCRIB antibody (ABIN7231292)

Target: SCRIB (Scribbled Homolog (SCRIB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCRIB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SCRIB Antibody

Purpose: SCRIB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SCRIB protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SCRIB protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SCRIB

Target: SCRIB (Scribbled Homolog (SCRIB))

Alternative Name: SCRIB

Background: Rabbit Anti-SCRIB Polyclonal Antibody,Protein scribble homolog, Scribble, hScrib, Protein LAP4,SCRIB gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.,SCRIB

Molecular Weight: observerd band 179kDa

Gene ID: 23513

UniProt: Q14160

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Tube Formation, Synaptic Vesicle Exocytosis, Asymmetric Protein Localization