SHPK antibody (AA 1-80)

Catalog No. ABIN7220788

This anti-SHPK antibody is a Rabbit Polyclonal antibody detecting SHPK in WB, ELISA and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for SHPK antibody (AA 1-80) (ABIN7220788)

Target: SHPK (Sedoheptulokinase (SHPK))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHPK antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SHPK Antibody

Binding Specificity: AA 1-80

Purpose: CARKL Polyclonal Antibody

Specificity: CARKL Polyclonal Antibody detects endogenous levels of CARKL protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human CARKL at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SHPK

Target: SHPK (Sedoheptulokinase (SHPK))

Alternative Name: CARKL

Background: Rabbit Anti-CARKL Polyclonal Antibody,SHPK, CARKL, Sedoheptulokinase, SHK, Carbohydrate kinase-like protein,The sedoheptulokinase encoded by SHPK has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.,Sedoheptulokinase

Molecular Weight: observerd band 55kDa

Gene ID: 23729

UniProt: Q9UHJ6

Pathways: Cellular Response to Molecule of Bacterial Origin