SH2D1B antibody (AA 40-120)
Quick Overview for SH2D1B antibody (AA 40-120) (ABIN7219370)
Target
See all SH2D1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 40-120
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Purpose
- EAT-2 Polyclonal Antibody
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Specificity
- EAT-2 Polyclonal Antibody detects endogenous levels of EAT-2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human EAT-2 at AA range: 40-120
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- SH2D1B (SH2 Domain Containing 1B (SH2D1B))
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Alternative Name
- EAT-2
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Background
- Rabbit Anti-EAT-2 Polyclonal Antibody,SH2D1B, EAT2, SH2 domain-containing protein 1B, EWS/FLI1-activated transcript 2, EAT-2,By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al. 2001 [PubMed 11689425]).,SH2 domain-containing protein 1B
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Gene ID
- 117157
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UniProt
- O14796
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
Target
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