SH2B3 antibody

Catalog No. ABIN7231342

This anti-SH2B3 antibody is a Rabbit Polyclonal antibody detecting SH2B3 in WB and ELISA. Suitable for Human.

Quick Overview for SH2B3 antibody (ABIN7231342)

Target: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH2B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SH2B3 Antibody

Purpose: SH2B3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SH2B3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SH2B3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SH2B3

Target: SH2B3 (SH2B Adaptor Protein 3 (SH2B3))

Alternative Name: SH2B3

Background: Rabbit Anti-SH2B3 Polyclonal Antibody,SH2B adapter protein 3, Lymphocyte adapter protein, Lymphocyte-specific adapter protein Lnk, Signal transduction protein Lnk,SH2B3 (SH2B Adaptor Protein 3) encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in SH2B3 have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for SH2B3.,SH2B3

Molecular Weight: observerd band 63kDa

Gene ID: 10019

UniProt: Q9UQQ2