SH3GLB2 antibody (AA 100-180)

Catalog No. ABIN7214742

This anti-SH3GLB2 antibody is a Rabbit Polyclonal antibody detecting SH3GLB2 in WB, ELISA and IHC (p). Suitable for Human, Mouse, Rat and Monkey.

Quick Overview for SH3GLB2 antibody (AA 100-180) (ABIN7214742)

Target: SH3GLB2 (SH3-Domain GRB2-Like Endophilin B2 (SH3GLB2))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3GLB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SH3GLB2 Antibody

Binding Specificity: AA 100-180

Purpose: Endophilin B2 Polyclonal Antibody

Specificity: Endophilin B2 Polyclonal Antibody detects endogenous levels of Endophilin B2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Endophilin B2 at AA range: 100-180

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SH3GLB2

Target: SH3GLB2 (SH3-Domain GRB2-Like Endophilin B2 (SH3GLB2))

Alternative Name: Endophilin B2

Background: Rabbit Anti-Endophilin B2 Polyclonal Antibody,SH3GLB2, KIAA1848, PP578, Endophilin-B2, SH3 domain-containing GRB2-like protein B2,The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.,Endophilin-B2

Molecular Weight: observerd band 48kDa

Gene ID: 56904

UniProt: Q9NR46