SIRPB1 antibody (AA 200-280)

Catalog No. ABIN7214046

The Rabbit Polyclonal anti-SIRPB1 antibody has been validated for WB and ELISA. It is suitable to detect SIRPB1 in samples from Human.

Quick Overview for SIRPB1 antibody (AA 200-280) (ABIN7214046)

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRPB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SIRPB1 Antibody

Binding Specificity: AA 200-280

Purpose: CD172b Polyclonal Antibody

Specificity: CD172b Polyclonal Antibody detects endogenous levels of CD172b protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CD172b at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SIRPB1

Target: SIRPB1 (Signal-Regulatory Protein beta 1 (SIRPB1))

Alternative Name: CD172b

Background: Rabbit Anti-CD172b Polyclonal Antibody,SIRPB1, Signal-regulatory protein beta-1, SIRP-beta-1, CD172 antigen-like family member B, CD antigen CD172b,Signal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for SIRPB1.,Signal-regulatory protein beta-1

Molecular Weight: observerd band 48kDa

Gene ID: 10326

UniProt: O00241