SUMO2/3 antibody (Cleaved-Gly93)

Catalog No. ABIN7212506

The Rabbit Polyclonal anti-SUMO2/3 antibody is suitable to detect SUMO2/3 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for SUMO2/3 antibody (Cleaved-Gly93) (ABIN7212506)

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO2/3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SUMO2/3 Antibody

Binding Specificity: AA 20-100, Cleaved-Gly93

Purpose: Cleaved-SUMO-2/3 (G93) Polyclonal Antibody

Specificity: Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human SUMO-2/3 at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SUMO2/3

Target: SUMO2/3 (Small Ubiquitin Related Modifier 2/3 (SUMO2/3))

Alternative Name: SUMO-2/3

Background: Rabbit Anti-Cleaved-SUMO-2/3 (G93) Polyclonal Antibody,SUMO2, SMT3A, SMT3H2, Small ubiquitin-related modifier 2, SUMO-2, HSMT3, SMT3 homolog 2, SUMO-3, Sentrin-2, Ubiquitin-like protein SMT3A, Smt3A,SUMO2 encodes small ubiquitin-like modifier 2 that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, small ubiquitin-like modifier 2 is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for SUMO2. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.,Small ubiquitin-related modifier 2

Molecular Weight: observerd band 11kDa

Gene ID: 6613

UniProt: P61956