SMG9 antibody (AA 70-150)

Catalog No. ABIN7231414

This Rabbit Polyclonal antibody specifically detects SMG9 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SMG9 antibody (AA 70-150) (ABIN7231414)

Target: SMG9 (Smg-9 Homolog, Nonsense Mediated mRNA Decay Factor (SMG9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMG9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMG9 Antibody

Binding Specificity: AA 70-150

Purpose: SMG9 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SMG9 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SMG9 protein at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SMG9

Target: SMG9 (Smg-9 Homolog, Nonsense Mediated mRNA Decay Factor (SMG9))

Alternative Name: SMG9

Background: Rabbit Anti-SMG9 Polyclonal Antibody,Protein SMG9,SMG9 (SMG9, Nonsense Mediated MRNA Decay Factor) is a Protein Coding gene. Diseases associated with SMG9 include Heart And Brain Malformation Syndrome. Among its related pathways are Gene Expression and Viral mRNA Translation. SMG9 encodes a regulatory subunit of the SMG1 complex, which plays a critical role in nonsense-mediated mRNA decay (NMD). Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity. Mutations in SMG9 cause a multiple congenital anomaly syndrome in human patients, characterized by brain malformation, congenital heart disease and other features.,SMG9

Molecular Weight: observerd band 57kDa

Gene ID: 56006

UniProt: Q9H0W8