SLC25A27 antibody (AA 110-190)

Catalog No. ABIN7232026

This Rabbit Polyclonal antibody specifically detects SLC25A27 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for SLC25A27 antibody (AA 110-190) (ABIN7232026)

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC25A27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SLC25A27 Antibody

Binding Specificity: AA 110-190

Purpose: UCP4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of UCP4 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human UCP4 protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SLC25A27

Target: SLC25A27 (Solute Carrier Family 25, Member 27 (SLC25A27))

Alternative Name: UCP4

Background: Rabbit Anti-UCP4 Polyclonal Antibody,Mitochondrial uncoupling protein 4 , UCP 4, Solute carrier family 25 member 27,SLC25A27 (Solute Carrier Family 25 Member 27) is a Protein Coding gene. Among its related pathways are Metabolism and Mitochondrial Uncoupling Proteins. Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of SLC25A27 are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.,UCP4

Molecular Weight: observerd band 35kDa

Gene ID: 9481

UniProt: O95847