Sortilin 1 antibody (AA 260-340)

Catalog No. ABIN7231448

The Rabbit Polyclonal anti-Sortilin 1 antibody has been validated for WB and ELISA. It is suitable to detect Sortilin 1 in samples from Human, Rat and Mouse.

Quick Overview for Sortilin 1 antibody (AA 260-340) (ABIN7231448)

Target: Sortilin 1 (SORT1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sortilin 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Sortilin 1 Antibody

Binding Specificity: AA 260-340

Purpose: SORT Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SORT protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SORT protein at AA range: 260-340

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Sortilin 1

Target: Sortilin 1 (SORT1)

Alternative Name: SORT

Background: Rabbit Anti-SORT Polyclonal Antibody,Sortilin, 100 kDa NT receptor, Glycoprotein 95, Gp95, Neurotensin receptor 3, NT3, NTR3,SORT1 encodes a member of the VPS10-related sortilin family of proteins. The encoded preproprotein is proteolytically processed by furin to generate the mature receptor. This receptor plays a role in the trafficking of different proteins to either the cell surface, or subcellular compartments such as lysosomes and endosomes. Expression levels of SORT1 may influence the risk of myocardial infarction in human patients. Alternative splicing results in multiple transcript variants.,SORT

Molecular Weight: observerd band 91kDa

Gene ID: 6272

UniProt: Q99523

Pathways: Neurotrophin Signaling Pathway